Luxury escapes

Luxury Hotels in Alton

We've selected 19 of the Best Luxury hotels in Alton for your 2026 vacation!

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High end Hotels in Alton

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9.3
Excellent
499 Reviews

From

130$/night

Drury Plaza Hotel St Louis Brentwood

8700 Eager Rd
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9
Excellent
1072 Reviews

From

118$/night

Country Inn & Suites By Radisson, St Charles Historic District

1190 South Main Street
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8.9
Excellent
640 Reviews

From

119$/night

Comfort Suites St Louis - Sunset Hills

3654 S. Lindbergh Blvd.
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Boutique luxury hotels in Alton

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8.8
Excellent
382 Reviews

From

97$/night

Best Western Plus Midamerica Hotel

9730 Hayden Drive
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9.2
Excellent
464 Reviews

From

209$/night

Live! By Loews - St. Louis

799 Clark Ave
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8.5
Very good
480 Reviews

From

71$/night

Sleep Inn & Suites O'Fallon Mo - Technology Drive

1147 Technology Drive
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10
Excellent
1 Reviews

From

170$/night

Homewood Suites By Hilton St Louis Westport

2434 Old Dorsett Road Homewood Suites By Hilton St. Louis Westport
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8.2
Very good
981 Reviews

From

134$/night

Angad Arts Hotel St. Louis, Tapestry Collection By Hilton

3550 Samuel Shepard Drive
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9.3
Excellent
77 Reviews

From

319$/night

Four Seasons St. Louis

999 North 2Nd Street
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7.9
Very good
806 Reviews

From

110$/night

Renaissance St. Louis Airport Hotel

9801 Natural Bridge Road
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7.7
Very good
627 Reviews

From

102$/night

Radisson Hotel Fairview Heights - St Louis

319 Fountains Parkway
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7.8
Very good
564 Reviews

From

146$/night

Comfort Suites St Charles-St Louis

1400 S. Fifth Street
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7.7
Very good
136 Reviews

From

99$/night

Quality Inn Near Six Flags St. Louis

1400 West Osage Street
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8.2
Very good
81 Reviews

From

149$/night

Mainstay Suites St Louis Airport

11225 Lone Eagle Dr. , Building B
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7.8
Very good
87 Reviews

From

121$/night

Doubletree By Hilton Collinsville/St.Louis

1000 Eastport Plaza Drive
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8.7
Excellent
515 Reviews

From

98$/night

The Wildwood Hotel

2801 Fountain Place
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7.5
Very good
242 Reviews

From

95$/night

Country Inn & Suites By Radisson, St Peters, Mo

3877 Veterans Memorial Parkway
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7.7
Very good
142 Reviews

From

134$/night

Crowne Plaza Hotel St. Louis Airport By Ihg

11228 Lone Eagle Drive
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8
Very good
232 Reviews

From

79$/night

Quality Inn Litchfield Route 66

1010 East Columbian N Blvd
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Location

Alton, Illinois, United States, 63144

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